Understanding Esketamine: The Science Behind Spravato
2 mins read

Understanding Esketamine: The Science Behind Spravato


Major depressive disorder (MDD) is a debilitating condition affecting millions of people worldwide. While traditional antidepressants can be very effective, a significant portion of individuals experience treatment-resistant depression (TRD). This means their symptoms persist despite trying multiple medications. Thankfully, there’s a new option for those struggling with TRD: Spravato (esketamine).

What is Spravato (esketamine)?

Spravato is a nasal spray medication containing esketamine, a different kind of antidepressant than traditional options. Unlike most medications that take weeks to show improvement, Spravato can offer rapid relief from depression symptoms in some patients, often within hours or days.

How Does Spravato Work?

The exact mechanism of how Spravato works is still being studied. However, it’s believed to interact with the brain’s glutamate system differently than traditional antidepressants. This may help to restore communication between brain cells and improve mood regulation.

Is Spravato Right for You?

Spravato is specifically for adults with TRD who haven’t found relief with other depression treatments. It’s important to note that Spravato is used in conjunction with an oral antidepressant medication, not as a standalone treatment.

Spravato Side Effects

Spravato can cause side effects, including dissociation (feeling disconnected from yourself or your surroundings), dizziness, nausea, and sedation. Because of these potential side effects, Spravato must be administered and monitored by a qualified healthcare professional in a certified clinic setting.

Alternatives for Treatment-Resistant Depression

If you’re interested in learning more about Spravato or exploring other alternatives for treatment-resistant depression, such as ketamine infusion therapy, consulting with a mental health professional is crucial. They can discuss your individual situation and determine the best course of treatment for you.

Take Control of Your TRD Today

Struggling with treatment-resistant depression doesn’t have to be your reality. Reach out to Anew Era TMS & Psychiatry now to explore your options.

Discover if Spravato could be the life-changing solution you’ve been waiting for.

Don’t let TRD stand in the way of your happiness—contact us today and start your journey toward a fulfilling life.



Leave a Reply

Your email address will not be published. Required fields are marked *